听力与言语-语言病理学

行为科学

医学伦理学

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  • Alcohol consumption and the CAGE test in outpatients with schizophrenia or schizoaffective disorder and in the general population.

    abstract::We conducted a survey of 151 outpatients with schizophrenia or schizoaffective disorder in Geneva, Switzerland, in 2000, and a mail survey in a representative sample of the general population of Geneva in 1996 (n = 742), to compare alcohol consumption and alcoholism in these two samples. Fewer patients with schizophre...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007144

    authors: Etter M,Etter JF

    更新日期:2004-01-01 00:00:00

  • The Schizophrenia Patient Outcomes Research Team (PORT): updated treatment recommendations 2003.

    abstract::Since publication of the original Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations in 1998, considerable scientific advances have occurred in our knowledge about how to help persons with schizophrenia. Today an even stronger body of research supports the scientific basis of treatment. This...

    journal_title:Schizophrenia bulletin

    pub_type: 指南,杂志文章,实务指引

    doi:10.1093/oxfordjournals.schbul.a007071

    authors: Lehman AF,Kreyenbuhl J,Buchanan RW,Dickerson FB,Dixon LB,Goldberg R,Green-Paden LD,Tenhula WN,Boerescu D,Tek C,Sandson N,Steinwachs DM

    更新日期:2004-01-01 00:00:00

  • Investigating graphesthesia task performance in the biological relatives of schizophrenia patients.

    abstract::This study compared the performance of 39 biological relatives of persons with schizophrenia to that of 30 normal adult controls on graphesthesia processing, a complex somatosensory processing task. The relatives performed significantly worse on the graphesthesia task compared to the healthy controls. The relatives an...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007082

    authors: Chang BP,Lenzenweger MF

    更新日期:2004-01-01 00:00:00

  • Stages of change in smokers with schizophrenia or schizoaffective disorder and in the general population.

    abstract::This study compared smoking behavior and motivation to quit smoking, assessed with a "stages of change" questionnaire, in outpatients with schizophrenia or schizoaffective disorder and in a representative sample of the general population. We conducted a mail survey in a representative sample of the general population ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007092

    authors: Etter M,Mohr S,Garin C,Etter JF

    更新日期:2004-01-01 00:00:00

  • Reduced red blood cell membrane essential polyunsaturated fatty acids in first episode schizophrenia at neuroleptic-naive baseline.

    abstract::There is emerging evidence in schizophrenia of membrane abnormalities, primarily reductions in the essential omega-3 and omega-6 series of polyunsaturated fatty acids (PUFA). Because previous studies have largely been in chronic patients, it is not known whether these membrane abnormalities also occur early in illness...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007140

    authors: Reddy RD,Keshavan MS,Yao JK

    更新日期:2004-01-01 00:00:00

  • The cognitive basis of disorganization symptomatology in schizophrenia and its clinical correlates: toward a pathogenetic approach to disorganization.

    abstract::This article focuses on the schizophrenic disorganization syndrome, which was initially described by Bleuler (who used the term "dissociation") as lying at the heart of schizophrenia. While adopting a neo-Bleulerian approach, we describe schizophrenic disorganization using a pathogenetic hypothesis and a three-part st...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007019

    authors: Hardy-Baylé MC,Sarfati Y,Passerieux C

    更新日期:2003-01-01 00:00:00

  • People with schizophrenia in five countries: conceptual similarities and intercultural differences in family caregiving.

    abstract::The European Psychiatric Services: Inputs Linked to Outcomes and Needs (EPSILON) study was a EU BIOMED-2-funded comparative, cross-national, cross-sectional study aimed (1) to produce standardized versions of five key research instruments in five languages, and (2) to compare the characteristics, needs, and life quali...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,多中心研究

    doi:10.1093/oxfordjournals.schbul.a007029

    authors: van Wijngaarden B,Schene A,Koeter M,Becker T,Knapp M,Knudsen HC,Tansella M,Thornicroft G,Vázquez-Barquero JL,Lasalvia A,Leese M,EPSILON Study Group.

    更新日期:2003-01-01 00:00:00

  • The Schizophrenia Care and Assessment Program Health Questionnaire (SCAP-HQ): an instrument to assess outcomes of schizophrenia care.

    abstract::Advances in treatment technologies and development of evidence-based standards of care demand better methods for routine assessment of outcomes for schizophrenia in systems of care. This article describes the development and psychometrics of a new instrument to assess outcomes of routine care for persons with schizoph...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007001

    authors: Lehman AF,Fischer EP,Postrado L,Delahanty J,Johnstone BM,Russo PA,Crown WH

    更新日期:2003-01-01 00:00:00

  • A review of cognitive training in schizophrenia.

    abstract::Empirically supported treatments for schizophrenia now include a variety of psychosocial interventions, such as social skills training, vocational rehabilitation, and psychotherapy. As awareness of the functional importance of neurocognitive impairments in schizophrenia has increased, interest in treatments to improve...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a007011

    authors: Twamley EW,Jeste DV,Bellack AS

    更新日期:2003-01-01 00:00:00

  • Creating school-age versions of semistructured interviews for the prodrome to schizophrenia: lessons from case reviews.

    abstract::There is an increasing emphasis on identifying individuals with schizophrenia earlier and earlier in their disease process, with the assumption that earlier identification translates into earlier treatment, which translates into improved outcome. Unfortunately, one age cohort, children under 13 years of age, have been...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a007042

    authors: Ross RG,Schaeffer J,Compagnon N,Heinlein S,Beresford C,Farley G

    更新日期:2003-01-01 00:00:00

  • Neurocognitive assessment in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project schizophrenia trial: development, methodology, and rationale.

    abstract::Patients with schizophrenia are severely impaired in crucial aspects of neurocognitive function. This impairment is the strongest clinical correlate of poor long-term outcome and adaptive dysfunction. Reports of neurocognitive enhancement with second generation antipsychotic medications have thus offered promise for i...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006990

    authors: Keefe RS,Mohs RC,Bilder RM,Harvey PD,Green MF,Meltzer HY,Gold JM,Sano M

    更新日期:2003-01-01 00:00:00

  • Psychological trauma and schizotypal symptoms.

    abstract::In a sample of 75 women recruited from the community, we measured trauma/maltreatment history and symptoms of schizotypal personality disorder, using both questionnaire and interview measures. As hypothesized, individuals with histories of trauma/maltreatment had elevated levels of schizotypal symptoms. Among types of...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006985

    authors: Berenbaum H,Valera EM,Kerns JG

    更新日期:2003-01-01 00:00:00

  • Characteristics of Korean-Americans with schizophrenia: a cross-ethnic comparison with African-Americans, Latinos, and Euro-Americans.

    abstract::The purpose of this study was (1) to identify the demographic and psychosocial characteristics of Korean-Americans with schizophrenia, and (2) to compare the demographic and psychosocial characteristics of Korean-Americans with schizophrenia to African-American, Latino, and Euro-American individuals with schizophrenia...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006974

    authors: Bae SW,Brekke JS

    更新日期:2002-01-01 00:00:00

  • Neurocognitive correlates of schizotypy in first degree relatives of schizophrenia patients.

    abstract::We examined neurocognitive correlates of three dimensions of schizotypy in 63 healthy first degree relatives of schizophrenia patients. Neurocognitive measures of attention, verbal memory, and prefrontal functioning were combined with self-report and interview measures of schizotypy. State-psychopathology (anxiety and...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006946

    authors: Vollema MG,Postma B

    更新日期:2002-01-01 00:00:00

  • Differences in age of first hospitalization for schizophrenia among immigrants and nonimmigrants in a national case registry.

    abstract::While previous studies have found an increased incidence of schizophrenia in some immigrant groups, differences in age of onset in these groups has not been examined. The purpose of this study was to compare age of first hospitalization of (1) native-born people versus immigrants, (2) immigrants from different countri...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006956

    authors: Rabinowitz J,Fennig S

    更新日期:2002-01-01 00:00:00

  • "Real world" atypical antipsychotic prescribing practices in public child and adolescent inpatient settings.

    abstract::This article examines the factors that influence antipsychotic use among youth treated in public inpatient facilities. By combining data from 11 focus groups, a survey of 43 researchers and clinicians, and a chart review of 100 closed patient charts, we investigated the interplay between physicians' and staff members'...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006913

    authors: Pappadopulos E,Jensen PS,Schur SB,MacIntyre JC 2nd,Ketner S,Van Orden K,Sverd J,Sardana S,Woodlock D,Schweitzer R,Rube D

    更新日期:2002-01-01 00:00:00

  • Antipsychotic prescribing practices in the Veterans Healthcare Administration--New York metropolitan region.

    abstract::Most research literature concerning pharmacological treatments reports results from controlled clinical trials, which provide data critical to assess the efficacy of new treatments in research populations. Fewer studies examine how treatments are adopted in everyday practice settings, where comorbid disorders and envi...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006924

    authors: Weissman EM

    更新日期:2002-01-01 00:00:00

  • Motivations that maintain substance use among individuals with psychotic disorders.

    abstract::This study quantitatively examined reasons for substance use among individuals with psychotic disorders and explored the relationship of these reasons to substance use problems and dependence. Sixty-nine people with psychotic disorders were interviewed using a battery of questionnaires called the Substance Use Scale f...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006934

    authors: Spencer C,Castle D,Michie PT

    更新日期:2002-01-01 00:00:00

  • The experience of schizophrenia: what's gender got to do with it? A critical review of the current status of research on schizophrenia.

    abstract::The role of gender in schizophrenia is explored, and literature on gender and schizophrenia is critically reviewed. The importance of investigating gender differences in schizophrenia is underscored by the lack of sufficient research in this area to date and the comparative neglect of sociocultural issues during the "...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a006944

    authors: Nasser EH,Walders N,Jenkins JH

    更新日期:2002-01-01 00:00:00

  • Contingency valuation and preferences of health states associated with side effects of antipsychotic medications in schizophrenia.

    abstract::The purpose of this study was to investigate the construct validity and the test-retest reliability of the willingness to pay (WTP) method for estimating health state preferences associated with side effects of antipsychotic medication. Ninety-six schizophrenia patients on antipsychotics were asked (1) how much they w...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006903

    authors: Sevy S,Nathanson K,Schechter C,Fulop G

    更新日期:2001-01-01 00:00:00

  • Detecting improvement in quality of life and symptomatology in schizophrenia.

    abstract::Instrument-based scores are often used as outcome measures. However, little is known about what changes in scores mean in terms of a clinical assessment of improvement or deterioration. The purpose of this report was to determine how much change in standard instrument scores represents a clinically detectable improvem...

    journal_title:Schizophrenia bulletin

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/oxfordjournals.schbul.a006869

    authors: Cramer J,Rosenheck R,Xu W,Henderson W,Thomas J,Charney D,Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia.

    更新日期:2001-01-01 00:00:00

  • Gender differences in poor outcome patients with lifelong schizophrenia.

    abstract::Gender effects have been reported quite consistently in schizophrenia, with male patients having an earlier age of onset, poorer functional outcome, greater negative symptoms and cognitive impairment, and less severe positive symptoms. Because age of onset, cognitive impairments, and negative symptoms are all correlat...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006850

    authors: Moriarty PJ,Lieber D,Bennett A,White L,Parrella M,Harvey PD,Davis KL

    更新日期:2001-01-01 00:00:00

  • Latent class analysis of DSM-IV schizotypal personality disorder criteria in psychiatric patients.

    abstract::The aim of the study was to evaluate the latent structure of DSM-IV schizotypal personality disorder (SPD) diagnostic criteria. The sample consisted of 564 consecutively admitted inpatients and outpatients. Exploratory latent class analysis identified a four-class model as the best fitting model for DSM-IV SPD criteri...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006860

    authors: Fossati A,Maffei C,Battaglia M,Bagnato M,Donati D,Donini M,Fiorilli M,Novella L

    更新日期:2001-01-01 00:00:00

  • Early brain wiring: activity-dependent processes.

    abstract::One of the leading theories of the neuropathology of schizophrenia is that it is a developmental disorder of "neural connectivity." To assess this theory, it is first necessary to understand how precise neural connections normally are established. Sensory-driven neural activity has been widely recognized as crucial fo...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a006880

    authors: Penn AA

    更新日期:2001-01-01 00:00:00

  • Disturbed circadian rest-activity cycles in schizophrenia patients: an effect of drugs?

    abstract::The circadian rest-activity cycle of schizophrenia patients stabilized for more than a year on monotherapy with a "classical" neuroleptic (haloperidol, flupentixol) or with the atypical neuroleptic clozapine was documented by continuous activity monitoring for 3-7 weeks. In this pilot study, the three patients treated...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a006890

    authors: Wirz-Justice A,Haug HJ,Cajochen C

    更新日期:2001-01-01 00:00:00

  • Maternal prepregnant body mass and risk of schizophrenia in adult offspring.

    abstract::This study examined the relation between maternal prepregnant body mass index (BMI) and development of schizophrenia and schizophrenia spectrum disorders in adult offspring from the Prenatal Determinants of Schizophrenia Study. The study drew on a previously studied cohort of births occurring between 1959 and 1967 to ...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033452

    authors: Schaefer CA,Brown AS,Wyatt RJ,Kline J,Begg MD,Bresnahan MA,Susser ES

    更新日期:2000-01-01 00:00:00

  • Schizophrenia research: a progress report, summarizing proceedings of the 1999 International Congress on Schizophrenia Research.

    abstract::The Seventh International Congress on Schizophrenia Research was held in Santa Fe, New Mexico, in April 1999. This was the largest Congress meeting to date, with almost 1,000 presentations that covered all aspects of schizophrenia research. This article provides an account of the Congress proceedings. Several research...

    journal_title:Schizophrenia bulletin

    pub_type:

    doi:10.1093/oxfordjournals.schbul.a033462

    authors: Buckley PF,Buchanan RW,Tamminga CA,Schulz SC

    更新日期:2000-01-01 00:00:00

  • Cognitive-behavioral therapy for medication-resistant symptoms.

    abstract::Cognitive-behavioral therapy for psychosis is described. It draws on the cognitive models and therapy approach of Beck and colleagues, combined with an application of stress-vulnerability models of schizophrenia and cognitive models of psychotic symptoms. There is encouraging evidence for the efficacy of this approach...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a033447

    authors: Garety PA,Fowler D,Kuipers E

    更新日期:2000-01-01 00:00:00

  • Substance use disorder in hospitalized severely mentally ill psychiatric patients: prevalence, correlates, and subgroups.

    abstract::The prevalence and demographic and clinical correlates of lifetime substance use disorders were examined in a cohort of 325 recently hospitalized psychiatric patients (53% schizophrenia or schizoaffective disorder). Alcohol use was the most common type of substance use disorder, followed by cannabis and cocaine use. U...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033438

    authors: Mueser KT,Yarnold PR,Rosenberg SD,Swett C Jr,Miles KM,Hill D

    更新日期:2000-01-01 00:00:00

  • The content and structure of schizotypy: a study using confirmatory factor analysis.

    abstract::This study examined the content of subscales within a multidimensional scale of self-reported schizotypy and their subsequent interrelationship by means of confirmatory factor analysis (CFA). Neither single-factor nor four-factor models provided good fits to the data; two-factor and three-factor models showed very goo...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033480

    authors: Venables PH,Rector NA

    更新日期:2000-01-01 00:00:00

  • Distress attributed to negative symptoms in schizophrenia.

    abstract::The purpose of the study was to examine (1) to which negative symptoms schizophrenia patients attribute distress and (2) whether clinical variables can predict the levels of reported distress. With the help of a research assistant, 86 hospitalized patients completed a self-rating scale for negative symptoms. The 21 it...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033490

    authors: Selten JP,Wiersma D,van den Bosch RJ

    更新日期:2000-01-01 00:00:00

  • Schizophrenia spectrum disorders in persons exposed to ionizing radiation as a result of the Chernobyl accident.

    abstract::We studied schizophrenia spectrum disorders in Chernobyl accident survivors by analyzing Chernobyl exclusion zone (EZ) archives (1986-1997) and by conducting a psychophysiological examination of 100 patients with acute radiation sickness (ARS) and 100 workers of the Chernobyl EZ who had worked as "liquidators-voluntee...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033492

    authors: Loganovsky KN,Loganovskaja TK

    更新日期:2000-01-01 00:00:00

  • Thought disorder in schizophrenia and mania: impaired context.

    abstract::This research studied hypotheses that positive thought disorder in schizophrenia is influenced by patients' not taking in immediate target contextual material, thereby losing vital cues that guide thought processes. We assessed 164 acute inpatients (including 55 schizophrenia and 31 bipolar disorder patients), using s...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033502

    authors: Harrow M,Green KE,Sands JR,Jobe TH,Goldberg JF,Kaplan KJ,Martin EM

    更新日期:2000-01-01 00:00:00

  • Changing attitudes about schizophrenia.

    abstract::Research on the effectiveness of short-term education programs in changing societal attitudes about mental illness has been mixed. Education efforts seem to be mediated by characteristics of the program participants. This study determines whether the effects of a specially prepared, semester-long course on severe ment...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033392

    authors: Holmes EP,Corrigan PW,Williams P,Canar J,Kubiak MA

    更新日期:1999-01-01 00:00:00

  • Structured Interview for Assessing Perceptual Anomalies (SIAPA).

    abstract::Clinical descriptions of perceptual and attentional anomalies in schizophrenia emphasize phenomena such as flooding, or inundation, by sensory stimuli. A failure of sensory "gating" mechanisms in the brain is hypothesized to account for these symptoms, and this hypothesis has led to a marked interest in their putative...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033402

    authors: Bunney WE Jr,Hetrick WP,Bunney BG,Patterson JV,Jin Y,Potkin SG,Sandman CA

    更新日期:1999-01-01 00:00:00

  • Race in the "decade of the brain".

    abstract::Despite NIMH efforts to facilitate the study of women and minorities in federally funded schizophrenia research, there is a significant lack of information about race differences in brain morphology and neuropsychological function in schizophrenia. A review of three major psychiatric journals between 1994 and 1996 rev...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033358

    authors: Lewine RR,Caudle J

    更新日期:1999-01-01 00:00:00

  • Neurocognitive and social functioning in schizophrenia.

    abstract::This cross-sectional study examined the relationships between neurocognitive and social functioning in a sample of 80 outpatients with DSM-III-R schizophrenia. The neurocognitive battery included measures of verbal ability, verbal memory, visual memory, executive functioning, visual-spatial organization, vigilance, an...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033363

    authors: Addington J,Addington D

    更新日期:1999-01-01 00:00:00

  • Cognitive rehabilitation for schizophrenia: problems, prospects, and strategies.

    abstract::Increasing awareness of the importance of neurocognitive impairments in schizophrenia has fostered considerable interest in the prospects for cognitive rehabilitation. Nevertheless, optimism has outpaced progress. We first review recent literature on the central assumptions that underlie cognitive rehabilitation, incl...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.schbul.a033377

    authors: Bellack AS,Gold JM,Buchanan RW

    更新日期:1999-01-01 00:00:00

  • Antipsychotics: Past and Future: National Institute of Mental Health Division of Services and Intervention Research Workshop, July 14, 1998.

    abstract::A workshop on "Antipsychotics: Past and Future" was convened by the National Institute of Mental Health (NIMH), Division of Services and Intervention Research (DSIR), on July 14, 1998, to review the results of recent antipsychotic drug research, discuss current standards of treatment, and identify areas needing furthe...

    journal_title:Schizophrenia bulletin

    pub_type:

    doi:10.1093/oxfordjournals.schbul.a033387

    authors: Dawkins K,Lieberman JA,Lebowitz BD,Hsiao JK

    更新日期:1999-01-01 00:00:00

  • Practice principles of cognitive enhancement therapy for schizophrenia.

    abstract::Cognitive Enhancement Therapy (CET) is a developmental approach to the rehabilitation of schizophrenia patients that attempts to facilitate an abstracting and "gistful" social cognition as a compensatory alternative to the more demanding and controlled cognitive strategies that often characterize schizophrenia as well...

    journal_title:Schizophrenia bulletin

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.schbul.a033411

    authors: Hogarty GE,Flesher S

    更新日期:1999-01-01 00:00:00

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